Citric Acid Fermentation by Aspergillus niger NG-110 in Shake Flask

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Effect of Additional Mineral Ions on Citric Acid Productivity by Aspergillus Niger Ng-110

The mutant strain of Aspergillus niger NG-110 was evaluated for the present investigation of citric acid production. The cultural conditions optimized during the course of study were pH and K4Fe(CN)6, K2HPO4 and CaCl2 concentrations. Cane-molasses was utilized as the basal fermentation medium. The mutant NG-110 produces maximal amount of citric acid when the pH of the medium was 6. When the con...

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In view of the often-cited theory that citric acid accumulation is caused by an inhibition of aconitase activity, the equilibrium of the reaction of aconitase was investigated by comparing in vivo steady-state concentrations of citrate and isocitrate in Aspergillus niger grown under various citric acid-producing conditions. With the equilibrium catalyzed by the A. niger enzyme in vitro, similar...

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Citric Acid Production by Aspergillus Niger*

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Acidic pre-treatment of sugarcane molasses for citric acid production by Aspergillus niger NG-4

Citric acid obtained through the microbial fermentation is considered synthetic while that of present in fruits is referred to as natural (Ranya et al., 1999; Karklins et al., 2001). It is responsible for the tart taste of various fruits e.g., lemons, limes, oranges, pineapples, pears and gooseberries. It can be extracted from the citrus fruit juice by adding calcium oxide to form calcium citra...

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Advances in citric acid fermentation by Aspergillus niger: biochemical aspects, membrane transport and modeling.

Citric acid is regarded as a metabolite of energy metabolism, of which the concentration will rise to appreciable amounts only under conditions of substantive metabolic imbalances. Citric acid fermentation conditions were established during the 1930s and 1940s, when the effects of various medium components were evaluated. The biochemical mechanism by which Aspergillus niger accumulates citric a...

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ژورنال

عنوان ژورنال: Journal of Biological Sciences

سال: 2003

ISSN: 1727-3048

DOI: 10.3923/jbs.2003.360.370